Routine Pediatric Surgical Emergencies: Incidence, Morbidity, and Mortality During the 1st 8000 Days of Life-A Narrative Review.

Alizeh Abbas, Ruth Laverde, Ava Yap, Caroline Q Stephens, Lubna Samad, Justina O Seyi-Olajide, Emmanuel A Ameh, Doruk Ozgediz, Kokila Lakhoo, Stephen W Bickler, John G Meara, Donald Bundy, Dean T Jamison, Greg Klazura, Alicia Sykes, Godfrey Sama Philipo

Journal: World journal of surgery 2023;47(12):3419-3428

PMID: 37341797

Abstract

BACKGROUND

Many potentially treatable non-congenital and non-traumatic surgical conditions can occur during the first 8000 days of life and an estimated 85% of children in low- and middle-income countries (LMICs) will develop one before 15 years old. This review summarizes the common routine surgical emergencies in children from LMICs and their effects on morbidity and mortality.

METHODS

A narrative review was undertaken to assess the epidemiology, treatment, and outcomes of common surgical emergencies that present within the first 8000 days (or 21.9 years) of life in LMICs. Available data on pediatric surgical emergency care in LMICs were aggregated.

RESULTS

Outside of trauma, acute appendicitis, ileal perforation secondary to typhoid fever, and intestinal obstruction from intussusception and hernias continue to be the most common abdominal emergencies among children in LMICs. Musculoskeletal infections also contribute significantly to the surgical burden in children. These "neglected" conditions disproportionally affect children in LMICs and are due to delays in seeking care leading to late presentation and preventable complications. Pediatric surgical emergencies also necessitate heavy resource utilization in LMICs, where healthcare systems are already under strain.

CONCLUSIONS

Delays in care and resource limitations in LMIC healthcare systems are key contributors to the complicated and emergent presentation of pediatric surgical disease. Timely access to surgery can not only prevent long-term impairments but also preserve the impact of public health interventions and decrease costs in the overall healthcare system.

© 2023. The Author(s).

Address: Department of Surgery, University of Alabama at Birmingham, Birmingham, AL, USA.; Department of Surgery, University of California San Francisco, San Francisco, CA, USA.; Department of Surgery, University of California San Francisco, San Francisco, CA, USA. [email protected].; Global Surgery Programs, Interactive Research & Development, Karachi, Pakistan.; Pediatric Surgical Unit, Lagos University Teaching Hospital, Lagos, Nigeria.; Division of Pediatric Surgery, Department of Surgery, National Hospital, Abuja, Nigeria.; Department of Pediatric Surgery, University of Oxford and Oxford University Hospitals, Oxford, UK.; Division of Pediatric Surgery, Department of Surgery, University of California San Diego School of Medicine, 9500 Gilman Drive #0739, La Jolla, San Diego, CA, 92093-0739, USA.; Program in Global Surgery and Social Change, Harvard Medical School, Boston, MA, USA.; Global Research Consortium for School Health and Nutrition, London School of Hygiene and Tropical Medicine, London, UK.; Institute for Global Health Sciences, University of California, San Francisco, San Francisco, CA, USA.; Loyola University Medical Center, Chicago, IL, USA.; Naval Medical Center San Diego, San Diego, CA, USA.; Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.
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