The regulatory functions of oxylipins in fungi: A review.

Huiqian Liu, Xizi Zhang, Wei Chen, Chengtao Wang

Journal: Journal of basic microbiology 2023;63(10):1073-1084

PMID: 37357952

Abstract

Quorum sensing (QS) is a communication mechanism between microorganisms originally found in bacteria. In recent years, an important QS mechanism has been discovered in the field of fungi, namely, the lipoxygenase compound oxylipin of arachidonic acid acts as a QS molecule in life cycle control, particularly in the sexual and asexual development of fungi. However, the role of oxylipins in mediating eukaryotic communication has not been previously described. In this paper, we review the regulatory role of oxylipins and the underlying mechanisms and discuss the potential for application in major fungi. The role of oxylipin as a fungal quorum-sensing molecule is the main focus of the review. Besides, the quorum regulation of fungal morphological transformation, biofilm formation, virulence factors, secondary metabolism, infection, symbiosis, and other physiological behaviors are discussed. Moreover, future prospectives and applications are elaborated as well.

Address: Key Laboratory of Geriatric Nutrition and Health, Ministry of Education, Beijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Engineering and Technology Research Center of Food Additives, School of Food and Health, Beijing Technology and Business University, Beijing, China.

DOI: 10.1002/jobm.202200721

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https://doi.org/10.1002/jobm.202200721

MeSH Terms: Fungi, Oxylipins, Quorum Sensing, Bacteria, Virulence Factors