Optical coherence tomography angiography: a review of the current literature.

Ahmed Javed, Aishwarya Khanna, Eleanor Palmer, Craig Wilde, Anwar Zaman, Gavin Orr, Dharmalingam Kumudhan, Arun Lakshmanan, Georgios D Panos

Journal: The Journal of international medical research 2023;51(7):3000605231187933

PMID: 37498178

Abstract

This narrative review presents a comprehensive examination of optical coherence tomography angiography (OCTA), a non-invasive retinal vascular imaging technology, as reported in the existing literature. Building on the coherence tomography principles of standard OCT, OCTA further delineates the retinal vascular system, thus offering an advanced alternative to conventional dye-based imaging. OCTA provides high-resolution visualisation of both the superficial and deep capillary networks, an achievement previously unattainable. However, image quality may be compromised by factors such as motion artefacts or media opacities, potentially limiting the utility of OCTA in certain patient cohorts. Despite these limitations, OCTA has various potential clinical applications in managing retinal and choroidal vascular diseases. Still, given its considerable cost implications relative to current modalities, further research is warranted to justify its broader application in clinical practice.

Address: Department of Ophthalmology, Queen's Medical Centre, Nottingham University Hospitals, Nottingham, United Kingdom.; Department of Ophthalmology, Royal Derby Hospital, Derby, United Kingdom.; Division of Ophthalmology and Visual Sciences, School of Medicine, University of Nottingham, Nottingham, United Kingdom.
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