Microbial astaxanthin: from bioprocessing to the market recognition.

Cassamo U Mussagy, Anna Kot, Laurent Dufossé, Carmem N D P Gonçalves, Jorge F B Pereira, Valeria C Santos-Ebinuma, Vijaya Raghavan, Adalberto Pessoa

Journal: Applied microbiology and biotechnology 2023;107(13):4199-4215

PMID: 37233757

Abstract

The attractive biological properties and health benefits of natural astaxanthin (AXT), including its antioxidant and anti-carcinogenic properties, have garnered significant attention from academia and industry seeking natural alternatives to synthetic products. AXT, a red ketocarotenoid, is mainly produced by yeast, microalgae, wild or genetically engineered bacteria. Unfortunately, the large fraction of AXT available in the global market is still obtained using non-environmentally friendly petrochemical-based products. Due to the consumers concerns about synthetic AXT, the market of microbial-AXT is expected to grow exponentially in succeeding years. This review provides a detailed discussion of AXT's bioprocessing technologies and applications as a natural alternative to synthetic counterparts. Additionally, we present, for the first time, a very comprehensive segmentation of the global AXT market and suggest research directions to improve microbial production using sustainable and environmentally friendly practices. KEY POINTS: • Unlock the power of microorganisms for high value AXT production. • Discover the secrets to cost-effective microbial AXT processing. • Uncover the future opportunities in the AXT market.

© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

Address: Escuela de Agronomía, Facultad de Ciencias Agronómicas Y de los Alimentos, Pontificia Universidad Católica de Valparaíso, 2260000, Quillota, Chile. [email protected].; Department of Food Biotechnology and Microbiology, Institute of Food Sciences, Warsaw University of Life Sciences, Nowoursynowska 159C, 02-776, Warsaw, Poland.; Chemistry and Biotechnology of Natural Products, CHEMBIOPRO, ESIROI Agroalimentaire, Université de La Réunion, 15 Avenue René Cassin, CS 92003, CEDEX 9, 97744, Saint-Denis, France.; CIEPQPF, Department of Chemical Engineering, Faculty of Sciences and Technology, University of Coimbra, Rua Sílvio Lima, Pólo II - Pinhal de Marrocos, 3030-790, Coimbra, Portugal.; Department of Bioprocess Engineering and Biotechnology, School of Pharmaceutical Sciences, São Paulo State University, Araraquara, São Paulo, 14800-903, Brazil.; Department of Bioresource Engineering, Faculty of Agricultural and Environmental Sciences, McGill University, Montreal, QC, Canada.; Department of Pharmaceutical-Biochemical Technology, School of Pharmaceutical Sciences, University of São Paulo, Butantã, São Paulo, Brazil.
Bant logo

© Copyright 2026, Nutrition Evidence

NED wishes to thank the following organisations for their support:

We use cookies to improve your experience and analyze site traffic with Google Analytics. By continuing to use our site, you agree to our use of cookies. Learn more.