Ketogenic diet in cancer management.

Asma Ismail Mahmod, Wamidh H Talib, Anfal Al-Dalaeen

Journal: Current opinion in clinical nutrition and metabolic care 2023;26(4):369-376

PMID: 37265176

Abstract

PURPOSE OF REVIEW

This review presents details about types of ketogenic diet (KD), anticancer mechanisms, and the use of KD in experimental and clinical studies. Studies summarized in this review provide a solid ground for researchers to consider the use of KD to augment conventional treatments.

RECENT FINDINGS

KD is a dietary pattern composed of high fat, moderate proteins, and very-low-carbohydrate. This diet was suggested to have an anticancer effect and to augment conventional anticancer therapies. KD can target cancer cell by interfering with its metabolism without harming normal cells.

SUMMARY

Several experimental and clinical studies support the use of KD as adjuvant therapy to treat different cancers.

Address: Faculty of Allied Medical Sciences.; Department of Clinical Nutrition and Dietetics, Faculty of Allied Medical Sciences.; Department of Clinical Pharmacy and Therapeutics, Applied Science Private University, Amman, Jordan.

DOI: 10.1097/MCO.0000000000000944

Link outs

Free resources

Medical:

https://medlineplus.gov/cancer.html

Research Materials:

https://antibodies.cancer.gov/detail/CPTC-BRIP1-5

Subscription / membership required

Full Text Sources:

MeSH Terms: Humans, Diet, Ketogenic, Diet, Carbohydrate-Restricted, Neoplasms, Dietary Carbohydrates