Nutrition paves the way to environmental toxicants and influences fetal development during pregnancy.

Arun Meyyazhagan, Haripriya Kuchi Bhotla, Valentina Tsibizova, Manikantan Pappuswamy, Aditi Chaudhary, Vijaya Anand Arumugam, Malek Al Qasem, Gian Carlo Di Renzo

Journal: Best practice & research. Clinical obstetrics & gynaecology 2023;89():102351

PMID: 37295316

Abstract

Nutrition plays a major role in the healthy pregnancy and development of the fetus. In addition, nutrition can expose humans to a wide range of potentially hazardous environmental constituents, such as organic pollutants and heavy metals from marine or agricultural food products while processing, producing, and packaging. Humans constantly face these constituents through air, water, soil, food, and domestic products. During pregnancy, the rate of cellular division and differentiation is higher; exposure to any of these environmental toxicants can lead to developmental defects as they cross the placental barrier and, in some cases, can harm the successive generation too, as some contaminants can act on the reproductive cells of the fetus (Diethylstilbestrol). Pregnant women are considered a vulnerable population to food contaminant exposure and require a proper dietary chart and conscious food choices. Food is a source of both essential nutrients and environmental toxicants. Here, we have researched the possible toxicants of the food industry and their influence on the fetus's in-utero development, along with the importance of dietary interventions and the need to balance a healthy diet to overcome the harms. The cumulative exposure to environmental toxicants can influence the mother's prenatal environment and affect the fetus's development.

Copyright © 2023 The Authors. Published by Elsevier Ltd.. All rights reserved.

Address: Perinatology Research Branch, Wayne State University, Detroit, USA; Centre of Perinatal and Reproductive Medicine, University of Perugia, Perugia, Italy; Department of Life Sciences, CHRIST (Deemed to be University), Bengaluru, 560029, Karnataka, India.; Department of Life Sciences, CHRIST (Deemed to be University), Bengaluru, 560029, Karnataka, India.; Department of Obstetrics and Gynecology, IM Sechenov First State University, Moscow, Russia; Almazov National Medical Research Centre, St Petersburg, Russia; PREIS International School, Firenze, Italy.; Department of Human Genetics and Molecular Biology, Bharathiar University, Coimbatore, 641046, Tamil Nadu, India.; Department of Obstetrics and Gynecology, Faculty of Medicine, Mutah University, Al-Karak, Jordan.; Perinatology Research Branch, Wayne State University, Detroit, USA; Centre of Perinatal and Reproductive Medicine, University of Perugia, Perugia, Italy; Department of Obstetrics and Gynecology, IM Sechenov First State University, Moscow, Russia; Almazov National Medical Research Centre, St Petersburg, Russia; PREIS International School, Firenze, Italy. Electronic address: [email protected].

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