The time to first treatment is an independent predictor of overall survival in chronic lymphocytic leukemia.

Address: Biotechnology Research Unit, Aprigliano, A.O./ASP of Cosenza, Cosenza, Italy.; Consiglio Nazionale delle Ricerche, Istituto di Fisiologia Clinica del CNR, Reggio Calabria, Italy.; Department of Cellular Biotechnologies and Hematology, "Sapienza" University, Rome, Italy.; Department of Hematology, Catholic University Hospital "A. Gemelli" Rome, Rome, Italy.; Department of Oncology and Hemato-oncology, University of Milano and Hematology CTMO, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.; Division of Haematology, Department of Translational Medicine, Università del Piemonte Orientale, Novara, Italy.; Oncology Institute of Southern Switzerland and Institute of Oncology Research, Bellinzona, Switzerland.; Hematology Unit of Reggio Calabria, Reggio Calabria, Italy.; Divisione di Ematologia, Ospedale Ferrarotto, Università di Catania, Catania, Italy.; Hematology Unit, Department of Onco-hematology, A.O. of Cosenza, Cosenza, Italy.; Ematologia, Dipartimento di Biomedicina e Prevenzione, Università degli Studi di Roma "Tor Vergata," Rome, Rome, Italy.; UO Molecular Pathology, Ospedale Policlinico San Martino IRCCS, Genoa, Italy.; Mutagenesis and Cancer Prevention Unit, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Clinical and Experimental Onco-Hematology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy.; Clinica Ematologica, Centro Trapianti e Terapie Cellulari, Azienda Ospedaliera Universitaria S. Maria Misericordia, Udine, Italy.; Haematology, University of Trieste, Trieste, Italy.; Hematology Unit, Azienda USL-IRCCS of Reggio Emilia, Reggio Emilia, Italy.; Scientific Directorate, Azienda USL-IRCCS of Reggio Emilia, Reggio Emilia, Italy.; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, Italy.