Pathogenic mechanism of infection.

Kun Lu, Yang Li, Rui Chen, Hua Yang, Yong Wang, Wei Xiong, Fang Xu, Qijun Yuan, Haihui Liang, Xian Xiao, Renqiang Huang, Zhipeng Chen, Chunou Tian, Songqing Wang

Journal: Future microbiology 2023;18():373-383

PMID: 37158065

Abstract

is a fatal, opportunistic human pathogen transmitted through the consumption of raw/undercooked seafood or direct contact. infection progresses rapidly and has severe consequences; some cases may require amputation or result in death. Growing evidence suggests that virulence factors and regulators play a large role in disease progression, involving host resistance, cellular damage, iron acquisition, virulence regulation and host immune responses. Its disease mechanism remains largely undefined. Further evaluation of pathogenic mechanisms is important for selecting appropriate measures to prevent and treat infection. In this review, the possible pathogenesis of infection is described to provide a reference for treatment and prevention.

Address: Department of Neurosurgery, First Naval Hospital of Southern Theater Command, Zhanjiang, 524000, China.; Department of Orthopedics, First Naval Hospital of Southern Theater Command, Zhanjiang, 524000, China.; Hemodialysis Center, First Naval Hospital of Southern Theater Command, Zhanjiang, 524000, China.

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