An Adaptive, Algorithm-based Text Message Intervention to Promote Health Behavior Adherence in Type 2 Diabetes: Treatment Development and Proof-of-Concept Trial.

Christopher M Celano, Christina Massey, Jessica Long, Sonia Kim, Olivia Velasquez, Brian C Healy, Deborah J Wexler, Elizabeth N Madva, Jeff C Huffman

Journal: Journal of diabetes science and technology 2023;17(2):364-373

PMID: 34911398

Abstract

BACKGROUND

Most individuals with type 2 diabetes (T2D) struggle to adhere to one or more health behaviors. Text message interventions (TMIs) have the potential to improve adherence but have had mixed effects on diet and activity in T2D. We developed an eight-week, adaptive, algorithm-driven TMI to promote physical activity, diet, self-care, and well-being. Then, in a single-arm trial, we assessed its feasibility, acceptability, and preliminary efficacy in 15 individuals with T2D and suboptimal adherence.

METHODS

Participants received daily text messages and were asked to rate the utility of each message (0=not helpful, 10=very helpful). These ratings were used by an algorithm to select subsequent messages based on each participant's prior ratings. We assessed intervention feasibility by rates of message transmission/response and acceptability through ratings of message utility and burden. Finally, we examined pre-post changes in diabetes self-care, diet, physical activity, and psychological outcomes and calculated effect sizes (Cohen's ).

RESULTS

All text messages were delivered, and participants provided ratings for 79% of messages, above our a priori thresholds for feasibility. Participants rated the individual messages and overall TMI as subjectively useful (utility: 8.1 [SD=2.1] and 7.8 [SD=2.0], respectively) and not burdensome (burden: 0.8 [SD=1.8]). The intervention led to significant, medium- to large-sized improvements in self-care (=0.77), diet (=0.99), and activity (=0.61) but minimal change in psychological outcomes.

CONCLUSIONS

The TMI was feasible and well-accepted, and it led to promising improvements in adherence-related outcomes. These findings should be confirmed in a larger randomized controlled trial.

Address: Department of Psychiatry, Harvard Medical School, Boston, MA, USA.; Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.; Maad, Ouakam Cité Batrain, Dakar, Senegal.; Harvard T.H. Chan School of Public Health, Boston, MA, USA.; Department of Psychiatry, McLean Hospital, Belmont, MA, USA.; Department of Neurology, Brigham and Women's Hospital, Boston, MA, USA.; Departments of Neurology and Biostatistics, Harvard Medical School, Boston, MA, USA.; Department of Medicine (Endocrinology), Harvard Medical School, Boston, MA, USA.; Diabetes Unit, Massachusetts General Hospital Diabetes Center, Boston, MA, USA.
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