Development in Fluorescent OFF-ON Probes Based on Cu Promoted Hydrolysis Reaction of the Picolinate Moiety.

Nadeem Ahmed, Wajeeha Zareen, Xiaopeng Yang, Zahid Shafiq, Yong Ye

Journal: Journal of fluorescence 2023;33(2):401-411

PMID: 36480123

Abstract

Anions and cations have a key role in our normal life. Cu ion is a crucial trace element accountable for the part of several cellular enzymes and proteins, including cytochrome c oxidase, dopamine monooxygenase, Cu/Zn superoxide dismutase, and ceruloplasmin. WHO has found the extreme acceptable level of Cu ions in drinking water is up to 2.0 ppm. Excess use of Cu ions is associated with various human genetic disorders. Thus, the visualization of Cu ions to avoid its toxic effects in chemical and biological systems is significant. In this review we have summarized sensors based on catalytic hydrolysis of picolinate to detect Cu ions. The sensors based on hydrolysis of picolinate are very selective as compared to the other sensors for Cu ions detection. We have focused on describing the structure, spectral properties, detection limits, and bioimaging model of the sensors.

Address: Phosphorus Chemical Engineering Research Center of Henan Province, College of Chemistry, Zhengzhou University, Zhengzhou, 450002, China.; Institute of Chemical Sciences, Bahauddin Zakariya University, Multan, 60800, Pakistan. [email protected].; Phosphorus Chemical Engineering Research Center of Henan Province, College of Chemistry, Zhengzhou University, Zhengzhou, 450002, China. [email protected].

DOI: 10.1007/s10895-022-03078-y

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https://doi.org/10.1007/s10895-022-03078-y

MeSH Terms: Humans, Copper, Hydrolysis, Cations, Fluorescent Dyes