Inborn errors of OAS-RNase L in SARS-CoV-2-related multisystem inflammatory syndrome in children.

Address: St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.; Paris City University, Imagine Institute, Paris, France.; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY, USA.; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.; Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.; Human Evolutionary Genetics Unit, Institut Pasteur, Paris City University, CNRS UMR 2000, Paris, France.; Doctoral College, Sorbonne University, Paris, France.; Laboratory of Immunology, Lyon Sud Hospital, Lyon, France.; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.; Paris City University, Imagine Institute, Paris, France.; Pediatric Intensive Care Department, Hospital Sant Joan de Déu, Barcelona, Spain.; Kids Corona Platform, Barcelona, Spain.; Center for Biomedical Network Research on Epidemiology and Public Health (CIBERESP), Instituto de Salud Carlos III, Madrid, Spain.; Department of Surgery and Surgical Specializations, Faculty of Medicine and Health Sciences, University of Barcelona, Barcelona, Spain.; Respiratory and Immunological Dysfunction in Pediatric Critically Ill Patients, Institute of Recerca Sant Joan de Déu, Barcelona, Spain.; Bursa City Hospital, Bursa, Turkey.; Ankara City Hospital, Yildirim Beyazit University, Ankara, Turkey.; Immunology and Rheumatology Division, Department of Pediatrics, University of Montreal, CHU Sainte-Justine, Montreal, QC, Canada.; Human Evolutionary Genetics Unit, Institut Pasteur, Paris City University, CNRS UMR 2000, Paris, France.; Center for Translational Research, Institut Pasteur, Paris City University, Paris, France.; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY, USA.; Department of Biochemistry and Center for RNA Science and Therapeutics, Case Western Reserve University, Cleveland, OH, USA.; Department of Surgery, Weill Cornell Medical College, New York, NY, USA.; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY, USA.; Department of Pediatrics, School of Medicine, Emory University, Atlanta, GA, USA.; International Center of Infectiology Research (CIRI), University of Lyon, INSERM U1111, Claude Bernard University, Lyon 1, CNRS, UMR5308, ENS of Lyon, Lyon, France.; Departments of Neurosurgery and Genetics and Yale Center for Genome Analysis, Yale School of Medicine, New Haven, CT, USA.; Department of Medical Genetics, School of Medicine, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey.; Department of Genetics, Yale University School of Medicine, New Haven, CT, USA.; Research Unit, Nuestra Señora de la Candelaria University Hospital, Santa Cruz de Tenerife, Spain.; Genomics Division, Institute of Technology and Renewable Energies (ITER), Granadilla de Abona, Spain.; CIBERES, ISCIII, Madrid, Spain.; Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, NIAID, NIH, Bethesda, MD, USA.; NIAID Clinical Genomics Program, NIH, Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, NIAID, NIH, Bethesda, MD, USA.; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.; Primary Immunodeficiencies Group, University of Antioquia (UdeA), Medellin, Colombia.; School of Microbiology, University of Antioquia (UdeA), Medellin, Colombia.; Neurometabolic Diseases Laboratory, IDIBELL-Hospital Duran I Reynals, CIBERER U759, ISIiii, Madrid, Spain.; Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, NIAID, NIH, Bethesda, MD, USA.; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Pediatrics Department, Hospital Sant Joan de Déu, Barcelona, Spain.; Department of Molecular Biology and Genetics, Bilkent University, Ankara, Turkey.; Department of Surgery and Surgical Specializations, Faculty of Medicine and Health Sciences, University of Barcelona, Barcelona, Spain.; Pediatric Rheumatology Division, Hospital Sant Joan de Déu, Barcelona, Spain.; Study Group for Immune Dysfunction Diseases in Children (GEMDIP), Institute of Recerca Sant Joan de Déu, Barcelona, Spain.; Department of Pediatrics, University Hospitals Leuven, Leuven, Belgium.; Department of General Pediatrics and Pediatric Infectious Diseases, Necker Hospital for Sick Children, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris City University, Paris, France.; Biodiversity and Epidemiology of Bacterial Pathogens, Pasteur Institute, Paris, France.; Department of Pediatric Cardiology, Necker Hospital for Sick Children, AP-HP, Paris City University, Paris, France.; Kids Corona Platform, Barcelona, Spain.; Department of Surgery and Surgical Specializations, Faculty of Medicine and Health Sciences, University of Barcelona, Barcelona, Spain.; Pediatrics Infectious Diseases Division, Hospital Sant Joan de Déu, Barcelona, Spain.; Infectious Diseases and Microbiome, Institute of Recerca Sant Joan de Déu, Barcelona, Spain.; Department of Molecular and Cellular Biology, National Center for Biotechnology (CNB-CSIC), Madrid, Spain.; Laboratory of Virology, Bichat-Claude Bernard Hospital, Paris, France.; Laboratory of Virology, AP-HP, Cochin Hospital, Paris, France.; Molecular Genetics Unit, Institute of Biomedicine of Valencia (IBV-CSIC), Valencia, Spain.; CIBERNED, ISCIII, Madrid, Spain.; Joint Research Unit in Neurology and Molecular Genetics, Institut of Investigation Sanitaria La Fe, Valencia, Spain.; Medical School, Paris City University, Paris, France.; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Bichat-Claude Bernard Hospital, Paris, France.; University Paris Diderot, Paris 7, UFR of Médecine-Bichat, Paris, France.; IAME, INSERM, UMRS1137, Paris City University, Paris, France.; Infectious and Tropical Diseases Department, AP-HP, Bichat-Claude Bernard Hospital, Paris, France.; Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden.; Department of Neuroscience and Experimental Therapeutics, Institute for Biomedical Research of Barcelona (IIBB), Spanish National Research Council (CSIC), Barcelona, Spain.; Institute for Biomedical Investigations August Pi i Sunyer (IDIBAPS), Barcelona, Spain.; Department of Pediatrics, University Hospitals Leuven and Laboratory for Inborn Errors of Immunity, KU Leuven, Leuven, Belgium.; Primary Immunodeficiency Research Laboratory, Center for Primary Immunodeficiency Ghent, Ghent University Hospital, Ghent, Belgium.; Neurometabolic Diseases Laboratory, IDIBELL-Hospital Duran I Reynals; and Catalan Institution for Research and Advanced Studies (ICREA), Barcelona, Spain.; CIBERER U759, ISCiii, Madrid, Spain.; Department of Paediatric Infectious Diseases and Virology, Imperial College London, London, UK.; Centre for Paediatrics and Child Health, Faculty of Medicine, Imperial College London, London, UK.; The American Genome Center, Collaborative Health Initiative Research Program, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.; Department of Anatomy, Physiology, and Genetics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.; Paris City University, Imagine Institute, Paris, France.; Study Center for Primary Immunodeficiencies, Necker Hospital for Sick Children, AP-HP, Paris, France.; New York Genome Center, New York, NY, USA.; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.; Paris City University, Imagine Institute, Paris, France.; Pediatric Hematology-Immunology and Rheumatology Unit, Necker Hospital for Sick Children, AP-HP, Paris, France.; Laboratory of Immunogenetics of Human Diseases, Innate Immunity Group, IdiPAZ Institute for Health Research, La Paz Hospital, Madrid, Spain.; Interdepartmental Group of Immunodeficiencies, Madrid, Spain.; Department of Clinical Sciences, University Fernando Pessoa Canarias, Las Palmas de Gran Canaria, Spain.; Department of Immunology, University Hospital of Gran Canaria Dr. Negrín, Canarian Health System, Las Palmas de Gran Canaria, Spain.; Department of Genetics, Yale University School of Medicine, New Haven, CT, USA.; Laboratory of Human Genetics and Genomics, The Rockefeller University, New York, NY, USA.; Kids Corona Platform, Barcelona, Spain.; Department of Surgery and Surgical Specializations, Faculty of Medicine and Health Sciences, University of Barcelona, Barcelona, Spain.; Study Group for Immune Dysfunction Diseases in Children (GEMDIP), Institute of Recerca Sant Joan de Déu, Barcelona, Spain.; Clinical Immunology and Primary Immunodeficiencies Unit, Pediatric Allergy and Clinical Immunology Department, Hospital Sant Joan de Déu, Barcelona, Spain.; Necmettin Erbakan University, Konya, Turkey.; Department of Pediatrics, Department of Microbiology, Immunology and Infectious Diseases, University of Montreal and Immunology and Rheumatology Division, CHU Sainte-Justine, Montreal, QC, Canada.; International Center of Infectiology Research (CIRI), University of Lyon, INSERM U1111, Claude Bernard University, Lyon 1, CNRS, UMR5308, ENS of Lyon, Lyon, France.; National Reference Center for Rheumatic, Autoimmune and Systemic Diseases in Children (RAISE), Pediatric Nephrology, Rheumatology, Dermatology Unit, Hospital of Mother and Child, Hospices Civils of Lyon, Lyon, France.; Human Evolutionary Genetics Unit, Institut Pasteur, Paris City University, CNRS UMR 2000, Paris, France.; Human Genomics and Evolution, Collège de France, Paris, France.; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.; Paris City University, Imagine Institute, Paris, France.; Department of Pediatrics, Necker Hospital for Sick Children, Paris, France.; Howard Hughes Medical Institute, The Rockefeller University, New York, NY, USA.