A review of the bioactive components and pharmacological properties of Lavandula species.

Gaber El-Saber Batiha, John Oluwafemi Teibo, Lamiaa Wasef, Hazem M Shaheen, Ayomide Peter Akomolafe, Titilade Kehinde Ayandeyi Teibo, Hayder M Al-Kuraishy, Ali I Al-Garbeeb, Athanasios Alexiou, Marios Papadakis

Journal: Naunyn-Schmiedeberg's archives of pharmacology 2023;396(5):877-900

PMID: 36773055

Abstract

Lavandula species is a flowering plant that is common in Europe and across the Mediterranean. Lavender has many health benefits for humans. In addition to its use in herbal medicine, it is widely used in the fields of cosmetics, perfumes, foods, and aromatherapy. Google Scholar, PubMed, Scopus, and Web of Science were used to search for relevant material on the phytochemical ingredients, the pharmacologic effects of the ingredients, and the mechanism of action of the Lavandula species identified. These materials were reviewed in order to have access to important updates about the Lavandula species. Lavender as referred to in English contains essential oils, anthocyanins, phytosterols, sugars, minerals, coumaric acid, glycolic acid, valeric acid, ursolic acid, herniarins, coumarins, and tannins. It has been used to treat colic and chest ailments, worrisome headaches, and biliousness, and in cleaning wounds. It has antifungal, antibacterial, neurologic, antimicrobial, anti-parasitic, anti-diabetic, and analgesic effects among others. Lavandula species has prospects for various biological applications, especially with its dermatological application. Advances in drug development would enable characterization of various bioactive constituents; thus, its development and application can have a more positive impact on humanity. Here, we highlighted updated information on the history, distribution, traditional uses, phytochemical components, pharmacology, and various biological activities of Lavandula species.

© 2023. The Author(s).

Address: Department of Pharmacology and Therapeutics, Faculty of Veterinary Medicine, Damanhour University, Damanhour, 22511, AlBeheira, Egypt. [email protected].; Department of Biochemistry and Immunology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil. [email protected].; Department of Pharmacology and Therapeutics, Faculty of Veterinary Medicine, Damanhour University, Damanhour, 22511, AlBeheira, Egypt.; Department of Biochemistry, University of Ibadan, Ibadan, Nigeria.; Department of Maternal-Infant and Public Health Nursing, College of Nursing, Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.; Department of Pharmacology, Toxicology and Medicine, Medical Faculty, College of Medicine, Al-Mustansiriyah University, P.O. Box 14132, Baghdad, Iraq.; Department of Science and Engineering, Novel Global Community Educational Foundation, Hebersham, NSW, 2770, Australia.; AFNP Med, 1030, Vienna, Austria.; Department of Surgery II, University Hospital Witten-Herdecke, Heusnerstrasse 40, University of Witten-Herdecke, 42283, Wuppertal, Germany. [email protected].
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