Characterizing the Heart and the Myocardium With Photon-Counting CT.

Emese Zsarnóczay, Akos Varga-Szemes, Tilman Emrich, Bálint Szilveszter, Niels R van der Werf, Domenico Mastrodicasa, Pál Maurovich-Horvat, Martin J Willemink

Journal: Investigative radiology 2023;58(7):505-514

PMID: 36822653

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Abstract

Noninvasive cardiac imaging has rapidly evolved during the last decade owing to improvements in computed tomography (CT)-based technologies, among which we highlight the recent introduction of the first clinical photon-counting detector CT (PCD-CT) system. Multiple advantages of PCD-CT have been demonstrated, including increased spatial resolution, decreased electronic noise, and reduced radiation exposure, which may further improve diagnostics and may potentially impact existing management pathways. The benefits that can be obtained from the initial experiences with PCD-CT are promising. The implementation of this technology in cardiovascular imaging allows for the quantification of coronary calcium, myocardial extracellular volume, myocardial radiomics features, epicardial and pericoronary adipose tissue, and the qualitative assessment of coronary plaques and stents. This review aims to discuss these major applications of PCD-CT with a focus on cardiac and myocardial characterization.

Address: From the Division of Cardiovascular Imaging, Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston.; Heart and Vascular Center, Semmelweis University, Budapest, Hungary.; Philips Healthcare, Best, the Netherlands.; Stanford University School of Medicine, Department of Radiology, California.; Medical Imaging Centre, Semmelweis University, Budapest, Hungary.

DOI: 10.1097/RLI.0000000000000956

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MeSH Terms: Phantoms, Imaging, Tomography, X-Ray Computed, Heart, Myocardium, Photons