Synovial fluid analysis: Relevance for daily clinical practice.

Francesca Oliviero, Brian F Mandell

Journal: Best practice & research. Clinical rheumatology 2023;37(1):101848

PMID: 37429800

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Abstract

Synovial fluid analysis can provide a prompt and definite diagnosis of crystal-induced arthritis, the most common acute inflammatory arthritis and a cause of chronic arthritis that may mimic rheumatoid, psoriatic, or peripheral spondyloarthritis. In many patients the diagnosis of gout or calcium pyrophosphate arthritis cannot be made with certainty without synovial fluid analysis. Additional information from fluid analysis can assist the clinician in honing the differential diagnosis of non-crystalline arthritis.

Address: Rheumatology Unit, Department of Medicine - DIMED, University of Padova, Padova, Italy. Electronic address: [email protected].; Department Rheumatologic and Immunologic Diseases, Chairman Department of Academic Medicine. Cleveland Clinic Lerner College of Medicine at Case Western Reserve University, Cleveland Clinic, Cleveland, Ohio, USA. Electronic address: [email protected].

DOI: 10.1016/j.berh.2023.101848

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MeSH Terms: Humans, Synovial Fluid, Uric Acid, Gout, Chondrocalcinosis, Calcium Pyrophosphate