The Molecular Weaponry Produced by the Bacterium in Foods.

José Ramos-Vivas, Olga Tapia, María Elexpuru-Zabaleta, Kilian Tutusaus Pifarre, Yasmany Armas Diaz, Maurizio Battino, Francesca Giampieri

Journal: Molecules (Basel, Switzerland) 2022;27(17):5585

PMID: 36080356

Abstract

is receiving increasing attention from both a medical and veterinary point of view, but the diversity of molecules it produces has made the interest in this bacterium extend to the field of probiotics, the microbiota, and above all, to its presence and action on consumer foods. The production of Acyl Homoserine Lactones (AHLs), a type of quorum-sensing (QS) signaling molecule, is the most often-studied chemical signaling molecule in Gram-negative bacteria. can use this communication mechanism to promote the expression of certain enzymatic activities in fermented foods, where this bacterium is frequently present. also produces a series of molecules involved in the modification of the organoleptic properties of different products, especially cheeses, where it shares space with other microorganisms. Although some strains of this species are implicated in infections in humans, many produce antibacterial compounds, such as bacteriocins, that inhibit the growth of true pathogens, so the characterization of these molecules could be very interesting from the point of view of clinical medicine and the food industry. Lastly, in some cases, is responsible for the production of biogenic amines or other compounds of special interest in food health. In this article, we will review the most interesting molecules that produce the strains and will discuss some of their properties, both from the point of view of their biological activity on other microorganisms and the properties of different food matrices in which this bacterium usually thrives.

Address: Research Group on Foods, Nutritional Biochemistry and Health, Universidad Europea del Atlántico, 39011 Santander, Spain.; Research Group on Foods, Nutritional Biochemistry and Health, Universidad Internacional Iberoamericana, Campeche 24560, Mexico.; CIBER of Infectious Diseases-CIBERINFEC, Instituto de Salud Carlos III, 28029 Madrid, Spain.; Department of Clinical Sciences, Polytechnic University of Marche, 60131 Ancona, Italy.; International Joint Research Laboratory of Intelligent Agriculture and Agri-Products Processing, Jiangsu University, Zhenjiang 212013, China.; Department of Biochemistry, Faculty of Sciences, King Abdulaziz University, Jeddah 80200, Saudi Arabia.
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