Endocrine Emergencies During Pregnancy: Diabetic Ketoacidosis and Thyroid Storm.

Odessa P Hamidi, Linda A Barbour

Journal: Obstetrics and gynecology clinics of North America 2022;49(3):473-489

PMID: 36122980

Full Text on Elsevier Science View on PubMed

Abstract

The physiologic changes and common signs and symptoms of pregnancy can make the early recognition of endocrine emergencies more challenging. Diabetic ketoacidosis (DKA) can occur at only modestly elevated glucose levels (euglycemic DKA), often accompanied by starvation ketosis due to substantial fetal-placental glucose demands and is associated with a high stillbirth rate. Thyroid storm is life threatening with a higher rate of heart failure and both require prompt and aggressive treatment to avoid maternal and fetal morbidity and mortality. Treatment of these disorders and the special considerations for recognition and management in the context of pregnancy are reviewed.

Address: University of Colorado, School of Medicine, Aurora, CO, USA. Electronic address: [email protected].; University of Colorado, School of Medicine, Aurora, CO, USA.

DOI: 10.1016/j.ogc.2022.02.003

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MeSH Terms: Diabetes Mellitus, Diabetic Ketoacidosis, Emergencies, Female, Glucose, Humans, Placenta, Pregnancy, Thyroid Crisis