Magnesium sulfate administration in difficult laryngoscopy: An effective and safe method.

Kamyar Iravani, Mehrdad Salari, Aida Doostkam, Farhad Mehrabi, Maryam Ghadimi

Journal: American journal of otolaryngology 2022;43(4):103479

PMID: 35525023

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Abstract

PURPOSE

Difficult laryngeal exposure during laryngeal microsurgery and laser surgery is a major concern for otolaryngologists. This study evaluated the efficacy and safety of magnesium sulfate administration in difficult laryngeal exposure patients.

STUDY DESIGN

Quasi-experimental design.

MATERIALS AND METHODS

Forty adult patients scheduled for laryngeal microsurgery with difficult laryngeal exposure according to Cormack-Lehane (CL) classification were included. Magnesium sulfate 50% (20-30 mg/kg) was administered as a bolus injection. Laryngeal exposure and hemodynamic stability were evaluated before and after the intervention.

RESULTS

CL grading was shown a statistically significant improvement after magnesium sulfate administration. There are no clinically significant changes in the mean arterial pressure, heart rate, and oxygen saturation levels in the patients who received magnesium sulfate for better laryngeal exposure.

CONCLUSION

Magnesium sulfate is an effective and safe drug for better viewing in difficult laryngeal exposure patients.

Address: Department of Otolaryngology, Otolaryngology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address: [email protected].; Department of Anesthesiology, Anesthesiology and Critical Care Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address: [email protected].; Shiraz Nephro-Urology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address: [email protected].; Department of Otolaryngology, Otolaryngology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address: [email protected].; Department of Anesthesiology, Anesthesiology and Critical Care Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address: [email protected].

DOI: 10.1016/j.amjoto.2022.103479

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MeSH Terms: Adult, Humans, Intubation, Intratracheal, Laryngoscopy, Larynx, Magnesium Sulfate, Research Design