Lingfung Chow, Haiyong Chen, Lixing Lao, Christian Xin Shuo Fang, Margaret Woon Man Fok, Bacon Fung Leung Ng, Katherine Tsang, Tracy Siuting Ho, Cody Yuenting Chu, Kinking Leung, Jetson Tszkit Ng, Grace Yagun Wen, Hanna Yufaye Chan, Kevin Kaifung Lun, Andrew Hokay Lau, Ho Ting, Zongshi Qin, Oliver Chunho Ma
Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology
2022;104():154254
Abstract
[{"label":"BACKGROUND","text":"Acupuncture has been an alternative approach for de Quervain's tenosynovitis (DQt), but trial evidence is still lacking."},{"label":"PURPOSE","text":"This study aimed to assess the efficacy of acupuncture in patients with DQt."},{"label":"STUDY DESIGN","text":"A randomized controlled trial."},{"label":"METHODS","text":"A total of 68 subjects with DQt were recruited from outpatients of Department of Orthopaedics and Traumatology, and Chinese medicine clinics, The University of Hong Kong, and were randomized into the acupuncture group (n\u00a0=\u00a034) and the waitlist group (n\u00a0=\u00a034). Subjects in the acupuncture group received 5 acupuncture sessions over 2 weeks, followed by a 10-week follow-up. The waitlist control group received assessments only in the first 6 weeks of the waiting period and received the same acupuncture treatment and follow-up as the treatment group in the next 12 weeks. The primary outcome was the general pain intensity using the Visual Analogue Scale (VAS) at the end of treatment (week 2). Secondary outcomes were grip and pinch strengths of affected hands, the quick Disabilities of the Arm, Shoulder and Hand Score (Q-DASH), and the World Health Organization Quality of Life-brief Questionnaire (WHOQOL-BREF) at weeks 2 and 6."},{"label":"RESULTS","text":"From baseline to 2 weeks, the mean VAS score decreased by 19.5 points in the acupuncture group and by 3.4 points in the waitlist group. The difference for acupuncture vs waitlist control was -16.2 points (95% CI, -26.7 to -5.6, p\u00a0=\u00a00.003). Acupuncture effects sustained for 10 weeks (mean difference compared with baseline, -30.6; 95% CI, -39.6 to -21.7). Secondary outcomes showed that acupuncture reduced pain intensity, improved grip and pinch strength of affected hands, and Q-DASH scores, but not the scores of WHOQOL-BREF in patients. No serious adverse event occurred during the study period."},{"label":"CONCLUSIONS","text":"Our findings support that 2-week of acupuncture is safe and effective in the reduction of pain intensity, and improvement of strengths and disabilities of hand in DQt patients. Acupuncture also has long-term effects on DQt."},{"label":"TRIAL REGISTRATION","text":"This study was registered at clinicaltrials.gov (NCT03472443)."},{"copyright":"Copyright \u00a9 2022 Elsevier GmbH. All rights reserved."}]
Address:
The Hong Kong Tuberculosis Association - The University of Hong Kong Chinese Medicine Clinic cum Training and Research Centre (Southern District), Hong Kong, China.; School of Chinese Medicine, The University of Hong Kong, Hong Kong, China.; The Chinese Medicine Department, Hospital Authority, Hong Kong, China.; Department of Orthopaedics and Traumatology, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China.; School of Chinese Medicine, The University of Hong Kong, Hong Kong, China; Virginia University of Integrative Medicine, Fairfax, USA.; School of Chinese Medicine, The University of Hong Kong, Hong Kong, China. Electronic address:
[email protected].