Biochemical testing to differentiate Cushing's disease from ectopic ACTH syndrome.

Amandine Ferriere, Antoine Tabarin

Journal: Pituitary 2022;25(5):705-708

PMID: 35759056

Abstract

The differential diagnosis of ACTH-dependent Cushing's syndrome is often a diagnostic challenge that has been debated in numerous studies. In this short article, we will discuss the performance and main drawbacks of the biochemical tests used for this diagnosis.

Address: Department of Endocrinology, Diabetes and Nutrition, CHU of Bordeaux and University of Bordeaux, 33604, Pessac, France.; Department of Endocrinology, Diabetes and Nutrition, CHU of Bordeaux and University of Bordeaux, 33604, Pessac, France. [email protected].

DOI: 10.1007/s11102-022-01241-z

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https://doi.org/10.1007/s11102-022-01241-z

MeSH Terms: Humans, ACTH Syndrome, Ectopic, Pituitary ACTH Hypersecretion, Cushing Syndrome, Adrenocorticotropic Hormone, Diagnosis, Differential, Petrosal Sinus Sampling, Corticotropin-Releasing Hormone