Reinforcing Interdisciplinary Collaborations to Unravel the Astrocyte "Calcium Code".

Ana Covelo, Anaïs Badoual, Audrey Denizot

Journal: Journal of molecular neuroscience : MN 2022;72(7):1443-1455

PMID: 35543801

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Abstract

In this review article, we present the major insights from and challenges faced in the acquisition, analysis and modeling of astrocyte calcium activity, aiming at bridging the gap between those fields to crack the complex astrocyte "Calcium Code". We then propose strategies to reinforce interdisciplinary collaborative projects to unravel astrocyte function in health and disease.

Address: Institut National de la Santé et de la Recherche Médicale (INSERM), U1215, NeuroCentre Magendie, 33077, Bordeaux, France.; University of Bordeaux, Bordeaux, 33077, France.; SERPICO Project-Team, Inria Centre Rennes-Bretagne Atlantique, Rennes Cedex, 35042, France.; SERPICO/STED Team, UMR144 CNRS Institut Curie, PSL Research University, Sorbonne Universités, Paris, 75005, France.; Computational Neuroscience Unit, Okinawa Institute of Science and Technology, Onna, 904-0495, Japan. [email protected].

DOI: 10.1007/s12031-022-02006-w

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MeSH Terms: Astrocytes, Calcium, Calcium Signaling