Prebiotic effect of fructans from on probiotic lactic acid bacteria and in children as a supplement for malnutrition.

Martinez-Gamiño Daniel, Garcia-Soto Mariano J, Gonzalez-Acevedo Olivia, Godinez-Hernandez Cesar, Juarez-Flores Bertha, Ortiz-Basurto Rosa Isela, Rodriguez-Aguilar Maribel, Flores-Ramirez Rogelio, Martinez-Martinez Marco, Ratering Stefan, Schnell Sylvia, Bach Horacio, Martinez-Gutierrez Fidel

Journal: Food & function 2022;13(7):4184-4193

PMID: 35322820

Abstract

An imbalanced gut microbiota predisposes the development of nutritional disorders and chronic gastrointestinal diseases. Several studies have shown improvements on the host's health by enhancing the microbiota with prebiotics that stimulate probiotic microorganisms. This study describes the prebiotic effect of fructans from consumed by children as a supplement for malnutrition. We report the extraction and degree of polymerization of fructans from , food safety and inflammatory analyses, and their effect on probiotic lactic acid bacteria (LAB). These fructans were included in the diet of 5-year-old normal-weight and malnourished children in double-blind, two-week interventions that compared the effects on their weight, bacterial count, and volatile organic compounds (VOCs). The extracted powdered fructans from had a composition comparable to inulin, were safe for human consumption, and stimulated the growth of three characteristic LAB. The children who consumed these fructans had a considerable weight gain, an increased number of LAB, and a decreased concentration of VOCs (indicative of less dysbiosis), demonstrating positive effects of this prebiotic on their microbiota, which were more significant in malnourished children. Fructans from induced in malnourished children significant weight gain and improved the functionality of their gut microbiota.

Address: Facultad de Ciencias Biológicas, Universidad Autónoma de Nuevo León, Mexico.; Facultad de Ciencias Químicas, Universidad Autónoma de San Luis Potosí, Manuel Nava 6, Zona Universitaria, San Luis Potosí, SLP 78210, Mexico. [email protected].; Facultad de Enfermería y Nutrición, Universidad Autónoma de San Luis Potosí, Mexico.; Instituto de Investigación de Zonas Desérticas, Universidad Autónoma de San Luis Potosí, Mexico.; Laboratorio Integral de Investigación en Alimentos, Instituto Tecnológico de Tepic, Mexico.; Coordinación para la Innovación y Aplicación de la Ciencia y la Tecnología, Universidad Autónoma de San Luis Potosí, Mexico.; Institut für Angewandte Mikrobiologie, Justus-Liebig-Universität Giessen, Germany.; Division of Infectious Diseases, Department of Medicine, University of British Columbia, Canada.; Centro de Investigación en Ciencias de la Salud y Biomedicina, Universidad Autónoma de San Luis Potosí, Mexico.

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