Approach to patients with hypertriglyceridemia.

Kenneth R Feingold, Alan Chait

Journal: Best practice & research. Clinical endocrinology & metabolism 2023;37(3):101659

PMID: 35459627

Full Text on Elsevier Science View on PubMed

Abstract

Elevated triglyceride levels increase the risk of arteriosclerotic cardiovascular disease (ASCVD) and severely elevated triglyceride levels also increase the risk of triglyceride-induced pancreatitis. Although substantially reducing triglyceride levels will prevent pancreatitis, whether lowering triglycerides per se will reduce CVD risk is unclear. In this review, we outline several principles that will help in deciding who and how to treat patients with elevated triglyceride levels in order to prevent both ASCVD and pancreatitis. Using these principles will help in making decisions regarding the treatment of elevated triglyceride levels.

Address: Department of Medicine, Division of Metabolism, Endocrinology and Nutrition, University of Washington, Seattle, WA, USA. Electronic address: [email protected].; University of California San Francisco, San Francisco, CA, USA. Electronic address: [email protected].

DOI: 10.1016/j.beem.2022.101659

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MeSH Terms: Humans, Hypertriglyceridemia, Pancreatitis, Triglycerides