Biosynthesis and biotechnological interventions for commercial production of microalgal pigments: A review.

Amit Srivastava, Mohneesh Kalwani, Hillol Chakdar, Sunil Pabbi, Pratyoosh Shukla

Journal: Bioresource technology 2022;352():127071

PMID: 35351568

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Abstract

Microalgae are photosynthetic eukaryotes that serve as microbial cell factories for the production of useful biochemicals, including pigments. These pigments are eco-friendly alternatives to synthetic dyes and reduce environmental and health risks. They also exhibit excellent anti-oxidative properties, making them a useful commodity in the nutrition and pharmaceutical industries. Light-harvesting pigments such as chlorophylls and phycobilins, and photoprotective carotenoids are some of the most common microalgal pigments. The increasing demand for these pigments in industrial applications has prompted a need to improve their metabolic yield in microalgal cells. So far, expensive cultivation methods and sensitivity to microbial contamination remain the main obstacles to the large-scale production of these pigments. This review highlights current issues and future prospects related to the production of microalgal pigments. The review also emphasizes the use of engineering approaches such as genetic engineering, and optimization of media components and physical parameters to increase their commercial-scale production.

Address: Department of Chemistry, Purdue University, West Lafayette, IN 47907, USA.; School of Biotechnology, Banaras Hindu University, Varanasi, Uttar Pradesh 221005, India; Centre for Conservation and Utilisation of Blue Green Algae (CCUBGA), Division of Microbiology, ICAR-Indian Agricultural Research Institute, New Delhi 110012, India.; ICAR-National Bureau of Agriculturally Important Microorganisms (NBAIM), Mau, Uttar Pradesh 275103, India.; Centre for Conservation and Utilisation of Blue Green Algae (CCUBGA), Division of Microbiology, ICAR-Indian Agricultural Research Institute, New Delhi 110012, India.; School of Biotechnology, Banaras Hindu University, Varanasi, Uttar Pradesh 221005, India. Electronic address: [email protected].

DOI: 10.1016/j.biortech.2022.127071

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MeSH Terms: Biotechnology, Carotenoids, Chlorophyll, Genetic Engineering, Microalgae