Esophageal Motility Disorders: Current Approach to Diagnostics and Therapeutics.

Dhyanesh A Patel, Rena Yadlapati, Michael F Vaezi

Journal: Gastroenterology 2022;162(6):1617-1634

PMID: 35227779

Abstract

Dysphagia is a common symptom with significant impact on quality of life. Our diagnostic armamentarium was primarily limited to endoscopy and barium esophagram until the advent of manometric techniques in the 1970s, which provided the first reliable tool for assessment of esophageal motor function. Since that time, significant advances have been made over the last 3 decades in our understanding of various esophageal motility disorders due to improvement in diagnostics with high-resolution esophageal manometry. High-resolution esophageal manometry has improved the sensitivity for detecting achalasia and has also enhanced our understanding of spastic and hypomotility disorders of the esophageal body. In this review, we discuss the current approach to diagnosis and therapeutics of various esophageal motility disorders.

Copyright © 2022 AGA Institute. Published by Elsevier Inc. All rights reserved.

Address: Division of Gastroenterology, Hepatology and Nutrition, Vanderbilt University Medical Center and Division of Gastroenterology, Nashville, Tennessee. Electronic address: [email protected].; University of California San Diego, San Diego, California.; Division of Gastroenterology, Hepatology and Nutrition, Vanderbilt University Medical Center and Division of Gastroenterology, Nashville, Tennessee.
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