Sarcopenic Dysphagia, Malnutrition, and Oral Frailty in Elderly: A Comprehensive Review.

Alessandro de Sire, Martina Ferrillo, Lorenzo Lippi, Francesco Agostini, Roberto de Sire, Paola Emilia Ferrara, Giuseppe Raguso, Sergio Riso, Andrea Roccuzzo, Gianpaolo Ronconi, Marco Invernizzi, Mario Migliario

Journal: Nutrients 2022;14(5):982

PMID: 35267957

Abstract

Frailty is a highly prevalent condition in the elderly that has been increasingly considered as a crucial public health issue, due to the strict correlation with a higher risk of fragility fractures, hospitalization, and mortality. Among the age-related diseases, sarcopenia and dysphagia are two common pathological conditions in frail older people and could coexist leading to dehydration and malnutrition in these subjects. "Sarcopenic dysphagia" is a complex condition characterized by deglutition impairment due to the loss of mass and strength of swallowing muscles and might be also related to poor oral health status. Moreover, the aging process is strictly related to poor oral health status due to direct impairment of the immune system and wound healing and physical and cognitive impairment might indirectly influence older people's ability to carry out adequate oral hygiene. Therefore, poor oral health might affect nutrient intake, leading to malnutrition and, consequently, to frailty. In this scenario, sarcopenia, dysphagia, and oral health are closely linked sharing common pathophysiological pathways, disabling sequelae, and frailty. Thus, the aim of the present comprehensive review is to describe the correlation among sarcopenic dysphagia, malnutrition, and oral frailty, characterizing their phenotypically overlapping features, to propose a comprehensive and effective management of elderly frail subjects.

Address: Department of Medical and Surgical Sciences, University of Catanzaro "Magna Graecia", 88100 Catanzaro, Italy.; Department of Health Sciences, University of Catanzaro "Magna Graecia", 88100 Catanzaro, Italy.; Department of Health Sciences, University of Eastern Piedmont "A. Avogadro", 28100 Novara, Italy.; Department of Anatomical and Histological Sciences, Legal Medicine and Orthopedics, Sapienza University, 00185 Rome, Italy.; Department of Clinical Medicine and Surgery, University Federico II of Naples, 80126 Naples, Italy.; University Polyclinic Foundation Agostino Gemelli IRCSS, Catholic University of Sacred Heart, 00168 Rome, Italy.; Department of Otolaryngology-Head and Neck Surgery, University of Verona, 37129 Verona, Italy.; Dietetic and Clinical Nutrition Unit, Maggiore della Carità Hospital, 28100 Novara, Italy.; Department of Periodontology, School of Dental Medicine, University of Bern, Freiburgstrasse 7, 3010 Bern, Switzerland.; Department of Oral and Maxillofacial Surgery, Copenhagen University Hospital (Rigshospitalet), 2100 Copenhagen, Denmark.; Translational Medicine, Dipartimento Attività Integrate Ricerca e Innovazione (DAIRI), Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo, 15121 Alessandria, Italy.; Dental Clinic, Department of Translational Medicine, University of Eastern Piedmont, 28100 Novara, Italy.
Bant logo

© Copyright 2026, Nutrition Evidence

NED wishes to thank the following organisations for their support:

We use cookies to improve your experience and analyze site traffic with Google Analytics. By continuing to use our site, you agree to our use of cookies. Learn more.