Circadian secretion rhythm of GLP-1 and its influencing factors.

Chuanfeng Liu, Yuzhao Liu, Yu Xin, Yangang Wang

Journal: Frontiers in endocrinology 2022;13():991397

PMID: 36531506

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Abstract

Circadian rhythm is an inherent endogenous biological rhythm in living organisms. However, with the improvement of modern living standards, many factors such as prolonged artificial lighting, sedentarism, short sleep duration, intestinal flora and high-calorie food intake have disturbed circadian rhythm regulation on various metabolic processes, including GLP-1 secretion, which plays an essential role in the development of various metabolic diseases. Herein, we focused on GLP-1 and its circadian rhythm to explore the factors affecting GLP-1 circadian rhythm and its potential mechanisms and propose some feasible suggestions to improve GLP-1 secretion.

Address: Department of Endocrinology, The Affiliated Hospital of Qingdao University, Qingdao, China.

DOI: 10.3389/fendo.2022.991397

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https://medlineplus.gov/sleepdisorders.html

MeSH Terms: Humans, Glucagon-Like Peptide 1, Circadian Rhythm, Sleep, Sleep Wake Disorders, Lighting