Lower Gastrointestinal Functional and Motility Disorders in Children.

Ricardo Arbizu, Ben Freiberg, Leonel Rodriguez

Journal: Pediatric clinics of North America 2021;68(6):1255-1271

PMID: 34736588

Full Text on Elsevier Science View on PubMed

Abstract

Functional and motility gastrointestinal disorders are the most common complaints to the pediatric gastroenterologist. Disorders affecting the small intestine carry a significant morbidity and mortality due to the severe limitation of therapeutic interventions available and the complications associated with such interventions. Congenital colorectal disorders are rare but also carry significant morbidity and poor quality of life plus the social stigma associated with its complications. In this review, we summarize the clinical presentation, diagnostic evaluations, and the therapeutic interventions available for the most common and severe gastrointestinal functional and motility disorders of the small bowel, colon, and anorectum.

Address: Section of Pediatric Gastroenterology, Hepatology and Nutrition, Pediatric Gastroenterology and Hepatology, Neurogastroenterology and Motility Center, Yale School of Medicine, Yale University School of Medicine, Yale New Haven Children's Hospital, 333 Cedar Street, LMP 4093, PO Box 208064, New Haven, CT 06520, USA.; Section of Pediatric Gastroenterology, Hepatology and Nutrition, Pediatric Gastroenterology and Hepatology, Neurogastroenterology and Motility Center, Yale School of Medicine, Yale University School of Medicine, Yale New Haven Children's Hospital, 333 Cedar Street, LMP 4093, PO Box 208064, New Haven, CT 06520, USA. Electronic address: [email protected].

DOI: 10.1016/j.pcl.2021.07.010

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MeSH Terms: Adolescent, Anorectal Malformations, Biopsy, Child, Child, Preschool, Colonic Diseases, Constipation, Erythromycin, Female, Gastrointestinal Diseases, Gastrointestinal Motility, Hirschsprung Disease, Humans, Infant, Intestinal Pseudo-Obstruction, Intestine, Small, Lower Gastrointestinal Tract, Male, Manometry, Nutritional Status, Quality of Life