Nutrition and bullous diseases.

Victoria Stoj, Jun Lu

Journal: Clinics in dermatology 2022;40(2):156-165

PMID: 34808244

Full Text on Elsevier Science View on PubMed

Abstract

Although relatively uncommon, autoimmune bullous diseases carry the risk of increased mortality and can significantly impact quality of life. This group of diseases is broad and encompasses subepidermal conditions such as bullous pemphigoid, cicatricial pemphigoid, epidermolysis bullosa acquisita, dermatitis herpetiformis, and linear IgA bullous dermatosis, as well as intraepidermal conditions such as pemphigus and its variants. The pathophysiology of each condition is incompletely understood but broadly involves the formation of autoantibodies targeting skin adhesion proteins, a process that relies on a complex interplay between a dysregulated immune system, genetic predisposition, and environmental factors. We review the impact of nutrition on pathogenesis, clinical course, and treatment of various autoimmune bullous diseases.

Address: University of Connecticut School of Medicine, Farmington, Connecticut, USA.; Department of Dermatology, University of Connecticut Health Center, Farmington, Connecticut, USA. Electronic address: [email protected].

DOI: 10.1016/j.clindermatol.2021.10.009

Link outs

Free resources

Medical:

https://medlineplus.gov/pemphigus.html

Miscellaneous:

https://assays.cancer.gov/CPTAC-1178

Subscription / membership required

Full Text Sources:

MeSH Terms: Autoimmune Diseases, Epidermolysis Bullosa Acquisita, Humans, Pemphigoid, Bullous, Pemphigus, Quality of Life, Skin Diseases, Vesiculobullous