Child Care Center Hand Hygiene Programs' Cost-Effectiveness in Preventing Respiratory Infections.

Ernestina Azor-Martinez, Leticia Garcia-Mochon, Monica Lopez-Lacort, Jenna Marie Strizzi, Francisco Javier Muñoz-Vico, Carmen Pilar Jimenez-Lorente, Maria Amparo Fernandez-Campos, Cristina Bueno-Rebollo, Guadalupe Del Castillo-Aguas, Josep Vicent Balaguer-Martinez, Francisco Gimenez-Sanchez

Journal: Pediatrics 2021;148(6):e2021052496

PMID: 34814193

Abstract

BACKGROUND

We previously demonstrated that a hand hygiene program, including hand sanitizer and educational measures, for day care center (DCC) staff, children, and parents was more effective than a soap-and-water program, with initial observation, in preventing respiratory infections (RIs) in children attending DCCs. We analyzed the cost-effectiveness of these programs in preventing RIs.

METHODS

A cluster, randomized, controlled and open study of 911 children aged 0 to 3 years, attending 24 DCCs in Almeria. Two intervention groups of DCC-families performed educational measures and hand hygiene, one with soap-and-water (SWG) and another with hand sanitizer (HSG). The control group (CG) followed usual hand-washing procedures. RI episodes, including symptoms, treatments, medical contacts, complementary analyses, and DCC absenteeism days, were reported by parents. A Bayesian cost-effectiveness model was developed.

RESULTS

There were 5201 RI episodes registered. The adjusted mean societal costs of RIs per child per study period were CG: €522.25 (95% confidence interval [CI]: 437.10 to 622.46); HSG: €374.53 (95% CI: 314.90 to 443.07); SWG: €494.51 (95% CI: 419.21 to 585.27). The indirect costs constituted between 35.7% to 43.6% of the total costs. Children belonging to the HSG had an average of 1.39 fewer RI episodes than the CG and 0.93 less than the SWG. It represents a saving of societal cost mean per child per study period of €147.72 and €119.15, respectively. The HSG intervention was dominant versus SWG and CG.

CONCLUSIONS

Hand hygiene programs that include hand sanitizer and educational measures for DCC staff, children, and parents are more effective and cost less than a program with soap and water and initial observation in children attending DCCs.

Copyright © 2021 by the American Academy of Pediatrics.

Address: Distrito Sanitario de Atención Primaria, Almería, Spain.; Escuela Andaluza de Salud Pública, University of Granada, Granada, Spain.; Center for Biomedical Research Network in Epidemiology and Public Health, Madrid, Spain.; Institute of Biomedical Research Granada, University Hospitals of Granada, University of Granada, Granada, Spain.; Vaccine Research Department, FISABIO-Public Health, Valencia, Spain.; Department of Public Health, University of Copenhagen, Copenhagen, Denmark.; Unidad de Inmunología, Hospital Torrecardenas, Almería, Spain.; Centro de Salud Colonia de Santa Ines, Distrito Sanitario de Atención Primaria Guadalhorce, Málaga, Spain.; CAP St Ildefons, Cornellà de Llobregat, Barcelona, Spain.; Instituto Hispalense de Pediatría, Instituto Balmis de Vacunas, Almeria, Spain.
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