Prevalence and Determinants of Vitamin D Deficiency in 9595 Mongolian Schoolchildren: A Cross-Sectional Study.

Jorick Bater, Sabri Bromage, Tuyatsetseg Jambal, Enkhjargal Tsendjav, Enkhsaikhan Lkhagvasuren, Yanjmaa Jutmann, Adrian R Martineau, Davaasambuu Ganmaa

Journal: Nutrients 2021;13(11):4175

PMID: 34836430

Abstract

Population-based data relating to vitamin D status of children in Northeast Asia are lacking. We conducted a cross-sectional study to determine the prevalence and determinants of vitamin D deficiency in 9595 schoolchildren aged 6-13 years in Ulaanbaatar (UB), the capital city of Mongolia. Risk factors for vitamin D deficiency were collected by questionnaire, and serum 25-hydroxyvitamin D (25[OH]D) concentrations were measured using an enzyme-linked fluorescent assay, standardized and categorized as deficient (25[OH]D <10 ng/mL) or not. Odds ratios for associations between independent variables and risk of vitamin D deficiency were calculated using multivariate analysis with adjustment for potential confounders. The prevalence of vitamins D deficiency was 40.6% (95% CI 39.7% to 41.6%). It was independently associated with female gender (adjusted odds ratio [aOR] for girls vs. boys 1.23, 95% CI 1.11-1.35), month of sampling (aORs for December-February vs. June-November 5.28 [4.53-6.15], March-May vs. June-November 14.85 [12.46-17.74]), lower levels of parental education (P for trend <0.001), lower frequency of egg consumption (P for trend <0.001), active tuberculosis (aOR 1.40 [1.03-1.94]), household smoking (aOR 1.13 [1.02 to1.25]), and shorter time outdoors (P for trend <0.001). We report a very high prevalence of vitamin D deficiency among Mongolian schoolchildren, which requires addressing as a public health priority.

Address: Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.; T School of Industrial Technology, Mongolian University of Science & Technology, Ulaanbaatar 14210, Mongolia.; The Mongolian Health Initiative, Ulaanbaatar 14210, Mongolia.; Ministry of Health, Ulaanbaatar 14210, Mongolia.; Department of Immunology, School of Biomedicine, Mongolian National University of Medical Sciences, Ulaanbaatar 14210, Mongolia.; Department of Math and Statistics, University of North Carolina at Charlotte, Charlootte, NC 28223, USA.; Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London E1 4NS, UK.; Channing Division of Network Medicine, Department of Medicine, Brigham and Wome's Hospital, Harvard Medical School, Boston, MA 02115, USA.
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