Genetic investigation of fibromuscular dysplasia identifies risk loci and shared genetics with common cardiovascular diseases.

Address: PARCC, INSERM, Université de Paris, F-750015, Paris, France.; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA.; Department of Human Genetics, University of Michigan Medical School, Ann Arbor, MI, USA.; Department of Neurology and Neurosurgery, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht, The Netherlands.; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, 55902, USA.; Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA.; Centre National de Recherche en Génomique Humaine, Institut de Génomique, CEA and Fondation Jean Dausset-CEPH, Evry, France.; PARCC, INSERM, Université de Paris, F-750015, Paris, France.; Hypertension Unit, Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou, F-75015, Paris, France.; Department of Anesthesiology, Michigan Medicine, University of Michigan, Ann Arbor, MI, USA.; Vascular Surgery Section, Department of Surgery, Michigan Medicine, University of Michigan, Ann Arbor, MI, 48109, USA.; Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Internal Medicine, Division of General Internal Medicine, Section Vascular Medicine, Maastricht University Medical Centre, Maastricht University, Maastricht, the Netherlands.; CARIM School for Cardiovascular Diseases, Maastricht University Medical Centre, Maastricht University, Maastricht, the Netherlands.; Heart and Vascular Institute, Cleveland Clinic, Cleveland, OH, 44195, USA.; Zena and Michael A. Wiener Cardiovascular Institute and Marie-Josée and Henry R, Kravis Center for Cardiovascular Health Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Human Genetics, University of Michigan Medical School, Ann Arbor, MI, USA.; Division of Cardiology, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, 1200, Brussels, Belgium.; Division of Internal Medicine and Hypertension Unit, Department of Medical Sciences, University of Turin, Turin, Italy.; Department of Hypertension, National Institute of Cardiology, Warsaw, Poland.; Department of Demography, University of Lodz, Lodz, Poland.; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, USA.; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1167 - RID-AGE - Labex DISTALZ - Risk factors and molecular determinants of aging-related disease, F-59000, Lille, France.; Department of Cardiovascular Diseases, Ghent University and Ghent University Hospital, Ghent, Belgium.; Department of Neurology, Bordeaux University Hospital, Inserm U1219, Bordeaux, France.; Department of Epidemiology, Cardiovascular Disease Prevention, and Health Promotion, National Institute of Cardiology, Warsaw, Poland.; Human Molecular Genetics, de Duve Institute, Université Catholique de Louvain, 1200, Brussels, Belgium.; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, 55902, USA.; Gonda Vascular Center, Mayo Clinic, Rochester, MN, 55902, USA.; Hypertension Unit, Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou, F-75015, Paris, France.; Université de Paris, Inserm, Centre d'Investigation Clinique 1418, F-75006, Paris, France.; PARCC, INSERM, Université de Paris, F-750015, Paris, France.; Department of Genetics, Assistance-Publiques-Hôpitaux de Paris, Hôpital Européen Georges Pompidou, F-75015, Paris, France.; Division of Cardiology, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, 1200, Brussels, Belgium.; Pole of Cardiovascular Research, Institut de Recherche Expérimentale et Clinique, Université Catholique de Louvain, 1200, Brussels, Belgium.; Zena and Michael A. Wiener Cardiovascular Institute and Marie-Josée and Henry R, Kravis Center for Cardiovascular Health Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Victor Chang Cardiac Research Institute, Darlinghurst, NSW, Australia.; St. Vincent's Clinical School, University of New South Wales, Sydney, NSW, Australia.; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA. [email protected].; Department of Human Genetics, University of Michigan Medical School, Ann Arbor, MI, USA. [email protected].; PARCC, INSERM, Université de Paris, F-750015, Paris, France. [email protected].