Metal insertion into NiFe-hydrogenases.

M Blokesch, A Paschos, E Theodoratou, A Bauer, M Hube, S Huth, A Böck

Journal: Biochemical Society transactions 2003;30(4):674-80

PMID: 12196162

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Abstract

The synthesis and the insertion of the metallocentre of NiFe-hydrogenases is a complex process, in which seven maturation enzymes plus ATP, GTP and carbamoyl phosphate are involved. The review summarizes what is known about the properties and activities of these auxiliary proteins, and postulates a pathway along which maturation may take place.

Address: Department Biologie I, Mikrobiologie, Universität München, Maria-Ward-Strasse 1a, D-80638 München, Germany.

DOI: 10.1042/bst0300674