TAp63 regulates bone remodeling by modulating the expression of TNFRSF11B/Osteoprotegerin.

Anna Maria Lena, Erica Foffi, Massimiliano Agostini, Mara Mancini, Margherita Annicchiarico-Petruzzelli, Daniel Aberdam, Tania Velletri, Yufang Shi, Gerry Melino, Ying Wang, Eleonora Candi

Journal: Cell cycle (Georgetown, Tex.) 2022;20(22):2428-2441

PMID: 34763601

Abstract

MSC, mesenchymal stem cells; OPG, osteoprotegerin; RUNX2, Run-trelated transcription factor 2.

Address: Department of Experimental Medicine, TOR, University of Rome "Tor Vergata", Rome, Italy.; IDI-IRCCS, Via dei Monti di Creta, Rome, IT.; University of Paris and INSERMU1138.; Cogentech Società Benefit Srl, Parco Scientifico E Tecnologico Della Sicilia, Catania, Italy.; Cas Key Laboratory of Tissue Microenvironment and Tumor, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.; The First Affiliated Hospital of Soochow University, Institutes for Translational Medicine, Soochow University, Suzhou, China.; Cas Key Laboratory of Tissue Microenvironment and Tumor, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.; Department of Experimental Medicine, TOR, University of Rome "Tor Vergata", Rome, Italy.; IDI-IRCCS, Via dei Monti di Creta, Rome, IT.
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