Strategies for dielectrophoretic separation in laboratory-on-a-chip systems.

Michael P Hughes

Journal: Electrophoresis 2003;23(16):2569-82

PMID: 12210160

Abstract

Dielectrophoresis--the induced motion of polarizable particles in nonuniform fields--has proven to be an effective method for the separation of bioparticles such as cells, viruses and proteins. In this paper, the application of dielectrophoresis in miniaturized laboratories-on-a-chip is discussed, and strategies are described for using dielectrophoresis both for the binary separation of bioparticles and for the fractionation of many populations in such devices.

Address: Centre for Biomedical Engineering, School of Engineering, University of Surrey, Guildford, Surrey GU2 7XH, United Kingdom. [email protected]

DOI: 10.1002/1522-2683(200208)23:16<2569::AID-ELPS2569>3.0.CO;2-M

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https://doi.org/10.1002/1522-2683(200208)23:16<256...

MeSH Terms: Cell Separation, Electrons, Electrophoresis, Capillary, Equipment Design, Ions, Macromolecular Substances, Miniaturization, Nanotechnology, Rheology