A review of topical vitamin C derivatives and their efficacy.

Christina D Enescu, Lisa M Bedford, Geoffrey Potts, Fatima Fahs

Journal: Journal of cosmetic dermatology 2022;21(6):2349-2359

PMID: 34559950

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Abstract

Vitamin C is a popular ingredient in over-the-counter cosmeceuticals due to its many biological functions in maintaining and improving skin health by treating UV damage, improving discoloration, and boosting collagen production. Several chemically modified derivatives of vitamin C have been developed in an attempt to increase the stability, percutaneous absorption, and overall activity of this ingredient in topical formulations. The goal of this review is to evaluate the differences between vitamin C derivatives that have been designed for cosmeceutical use and their efficacy.

Address: School of Medicine, Wayne State University, Detroit, MI, USA.; Department of Dermatology, Wayne State University, Detroit, MI, USA.

DOI: 10.1111/jocd.14465

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MeSH Terms: Ascorbic Acid, Cosmeceuticals, Humans, Skin, Skin Absorption, Skin Aging, Vitamins