Cutaneous Polymer-Coating Embolism After Endovascular Procedures: Report of Two Cases and a Literature Review.

Mario Berríos-Hernández, Charigan Abou-Jokh Casas, Laura Sainz-Gaspar, Javier Ginarte-Val, Virginia Fernández Redondo, Diego López-Otero, Carlos Aliste, Jose M Suárez-Peñaranda

Journal: The American Journal of dermatopathology 2022;43(9):662-666

PMID: 33606376

Abstract

Different hydrophilic and hydrophobic polymers are used as lubricious coatings to reduce vascular traumas in minimally invasive percutaneous procedures. Although they are usually very safe, there is still a risk of serious complications in patients undergoing such procedures, mostly derived from the devices' coating detachment and systemic embolization. The lungs are the most common organ involved, followed by the central nervous system. Yet, cutaneous embolization is unusual, and only 19 cases are available in the literature. Most commonly, they present as asymptomatic retiform purpura on the lower legs, which tends to involve spontaneously. Correct clinical diagnosis is not suspected in most cases, being cholesterol emboly or vasculitis the preferred options. Time interval since surgical procedure and appearance of lesions vary widely but they generally start in the first few days. Histopathological identification of the embolus as bluish, amorphous intraluminal material in dermal vessels is diagnostic, but vasculitic signs are not present. We report 2 cases of skin lesions as the main manifestation of polymer embolization after endovascular surgical procedures. In both cases, biopsy allowed identification of embolized foreign material and lesions resolved without specific treatment.

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Address: Departments of Pathology.; Cardiology, and.; Dermatology, Clinical University Hospital, Santiago de Compostela, Spain ; and.; Departments of Dermatology, and.; Forensic Sciences and Pathology, Faculty of Medicine, University of Santiago de Compostela.
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