A practical approach to normocalcemic primary hyperparathyroidism.

José Luis Muñoz de Nova, Miguel Sampedro-Nuñez, Isabel Huguet-Moreno, Mónica Marazuela Azpiroz

Journal: Endocrine 2021;74(2):235-244

PMID: 34386939

Abstract

Normocalcemic primary hyperparathyroidism is an entity on which several issues about its clinical management remains unclear. This is reflected in the main current guidelines, where there are no evidence-based specific recommendations. Through an exhaustive review of current literature, a clinical management algorithm for these patients is proposed. We consider the diagnosis criteria, the differential diagnosis, the clinical manifestations, and the treatment indications. When indicated, we also review the preoperative locations techniques and the surgical approach. Finally, when surgical treatment is not indicated, the patient is not a candidate to surgery or refuse surgical management, we review the medical treatment options and the follow-up schemes.

© 2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

Address: Department of General and Digestive Surgery, Hospital Universitario de la Princesa; Instituto de Investigación Sanitaria Princesa (ISS-IP); Universidad Autónoma de Madrid, Madrid, Spain.; Department of Endocrinology and Nutrition, Hospital Universitario de la Princesa; Instituto de Investigación Sanitaria Princesa (ISS-IP); Universidad Autónoma de Madrid, Madrid, Spain.; Department of Endocrinology and Nutrition, Hospital Universitario Infanta Leonor, Madrid, Spain.; Department of Endocrinology and Nutrition, Hospital Universitario de la Princesa; Instituto de Investigación Sanitaria Princesa (ISS-IP); Universidad Autónoma de Madrid, Madrid, Spain. [email protected].

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