Erythroderma (exfoliative dermatitis). Part 2: energy homeostasis and dietetic management strategies.

S Tso, H Moiz, F Satchwell, T Hari, S Dhariwal, R Barlow, E Forbat, I C Blee, Y T Tan, C Thind, A Ilchyshyn, H Randeva, M M Kwok, A C Y Tso, T M Barber

Journal: Clinical and experimental dermatology 2021;46(6):1011-1015

PMID: 33817816

Abstract

["Erythroderma (exfoliative dermatitis) is associated with important metabolic changes that include an enhancement in energy expenditure. The key components to total energy expenditure (TEE) include basal metabolic rate (~68% of TEE), physical activity (~22% of TEE) and thermic effect of food (~10% of TEE). In the erythrodermic state, there are likely multiple contributors to the increase in basal metabolic rate, such as 'caloric drain' resulting from increased evaporation of water from enhanced transepidermal water loss, increased activity of the cardiovascular system (including high-output cardiac failure), increased nonshivering thermogenesis and hormonal changes such as hypercortisolaemia. A change in the patient's level of physical activity and appetite as a result of ill health status may further impact on their TEE and energy consumption. In Part 2 of this two-part concise review, we explore the key constituents of energy homeostasis and the potential mechanisms influencing energy homeostasis in erythroderma, and suggest much-needed dietetic management strategies for this important condition.",{"copyright":"\u00a9 2021 British Association of Dermatologists."}]
Address: Jephson Dermatology Centre, South Warwickshire NHS Foundation Trust, Warwick, UK.; Department of Public Health, University of Warwick, Coventry, UK.; University of Buckingham Medical School, Buckingham, UK.; Department of Dermatology, University Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK.; Centre for Host Microbiome Interactions King's College London, London, UK.; Department of Cardiology, South Warwickshire NHS Foundation Trust, Warwick, UK.; Warwickshire Institute for the Study of Diabetes, Endocrinology and Metabolism, University Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK.; Warwick Medical School, University of Warwick, Warwick, UK.; Department of Anesthetics, Westmead Hospital, Sydney, NSW, Australia.; Department of Haematology, Tan Tock Seng Hospital, Singapore, Singapore.
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