Comprehensive review of diagnostic modalities for early chronic pancreatitis.

Qi-Chao Ge, Christoph F Dietrich, Manoop S Bhutani, Bao-Zhen Zhang, Yue Zhang, Yi-Dan Wang, Jing-Jing Zhang, Yu-Fan Wu, Si-Yu Sun, Jin-Tao Guo

Journal: World journal of gastroenterology 2021;27(27):4342-4357

PMID: 34366608

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Abstract

Chronic pancreatitis (CP) is a progressive condition caused by several factors and characterised by pancreatic fibrosis and dysfunction. However, CP is difficult to diagnose at an early stage. Various advanced methods including endoscopic ultrasound based elastography and confocal laser endomicroscopy have been used to diagnose early CP, although no unified diagnostic standards have been established. In the past, the diagnosis was mainly based on imaging, and no comprehensive evaluations were performed. This review describes and compares the advantages and limitations of the traditional and latest diagnostic modalities and suggests guidelines for the standardisation of the methods used to diagnose early CP.

Address: Department of Gastroenterology, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning Province, China.; Department Allgemeine Innere Medizin, Salem und Permanence, Bern CH-3000, Switzerland.; Department of Gastrointestinal, Hepatology and Nutrition, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, United States.; Department of Gastroenterology, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning Province, China. [email protected].

DOI: 10.3748/wjg.v27.i27.4342

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https://assays.cancer.gov/CPTAC-660

MeSH Terms: Elasticity Imaging Techniques, Endosonography, Humans, Pancreatic Diseases, Pancreatitis, Chronic