Diet and physical activity in Greenland: genetic interactions and associations with obesity and diabetes.

Ninna Karsbæk Senftleber, Maria Overvad, Inger Katrine Dahl-Petersen, Peter Bjerregaard, Marit Eika Jørgensen

Journal: Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 2022;46(8):849-855

PMID: 34107227

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Abstract

The Inuit in Greenland have gone through dramatic lifestyle changes during the last half century. More time is spent being sedentary and imported foods replaces traditional foods like seal and whale. The population has also experienced a rapid growth in obesity and metabolic disturbances and diabetes is today common despite being almost unknown few decades ago. In this paper, we describe and discuss the role of lifestyle changes and genetics for Inuit metabolic health. Cardiometabolic disease risk has increased in Greenland. Lifestyle changes and possibly gene-lifestyle interactions play a role.

Address: Steno Diabetes Center Copenhagen, Gentofte, Denmark.; National Institute of Public Health, Southern Denmark University, Copenhagen, Denmark.; University of Greenland, Nuuk, Greenland.

DOI: 10.1139/apnm-2021-0020

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MeSH Terms: Diabetes Mellitus, Type 2, Diet, Exercise, Genetic Predisposition to Disease, Greenland, Health Surveys, Humans, Inuit, Obesity, Sedentary Behavior