Bioactive components from seeds: production, functionalities and applications - a critical review.

Christian K O Dzuvor, Sharadwata Pan, Charles Amanze, Prosper Amuzu, Charles Asakiya, Francis Kubi

Journal: Critical reviews in biotechnology 2022;42(2):271-293

PMID: 34151645

Abstract

A readily distinguishable and indigenous member of the plant kingdom in the Indian subcontinent is the 'drumstick tree', i.e. Lam. In addition to India, this drought-tolerant and rapidly evolving tree is currently extensively disseminated across the globe, including subtropical and tropical areas. The plant boasts a high nutritional, nutraceutical and therapeutic profile, mainly attributing to its significant repertoire of the biologically active components in different parts: protein, flavonoids, saponins, phenolic acids, tannin, isothiocyanate, lipids, minerals, vitamins, amongst others. seeds have been shown to elicit a myriad of pharmacological potential and health benefits, including: antimicrobial, anticancer, antidiabetic, antioxidant, antihypertensive, anti-inflammatory and cardioprotective properties. Additionally, the seed cakes obtained from post-extraction process are utilized for: coagulation, flocculation and sedimentation purposes, benefiting effluent management and the purification of water, mainly because of their capability in eliminating microbes and organic matter. Despite the extraordinary focus on other parts of the plant, especially the foliage, the beneficial aspects of the seeds have not been sufficiently highlighted. The health benefits of bioactive components in the seeds are promising and demonstrate enough potential to facilitate the development of functional foods. In this review, we present a critical account of the types, characteristics, production and isolation of bioactive components from seeds. Furthermore, we appraise the: pharmacological activities, cosmetic, biodiesel, lubricative, modern farming, nutritive and wastewater treatment applications of these functional ingredients. We infer that there is a need for further human/clinical studies and evaluation, despite their health benefits. Additionally, the safety issues need to be adequately clarified and assessed, in order to establish a conventional therapeutic profile.

Address: Bioengineering Laboratory, Department of Chemical Engineering, Monash University, Melbourne, Australia.; TUM School of Life Sciences, Technical University of Munich, Freising, Germany.; School of Minerals Processing and Bioengineering, Central South University, Changsha, Hunan, China.; School of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang, P R China.; Key Laboratory of Precision Nutrition and Food Quality, Department of Nutrition and Health, China Agricultural University, Beijing, China.; Department of Chemical Engineering, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.

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