Lupus retinopathy: epidemiology and risk factors.

Leonardo Gomes Bortoloti de Azevedo, Ana Luiza Biancardi, Renata Alves Silva, Nycholas da Costa Tavares, Mirhelen Mendes de Abreu, Blanca Elena Rios Gomes Bica, Haroldo Vieira de Moraes

Journal: Arquivos brasileiros de oftalmologia 2021;84(4):395-401

PMID: 34287516

Abstract

Lupus retinopathy is a clinical manifestation of systemic lupus erythematosus in the visual system. It is generally asymptomatic; however, it can become a threatening condition. It is closely associated with the inflammatory activity and higher mortality of systemic lupus erythematosus. Lupus retinopathy has several different clinical presentations, such as lupus microangiopathy, vascular occlusion, vasculitis, hypertensive retinopathy associated with lupus nephritis, and autoimmune retinopathy. Although the prevalence and associated factors of lupus retinopathy have been well defined in some parts of the world, there are no data from Latin America, including Brazil. As lupus retinopathy is generally asymptomatic, without a routine fundoscopy, it has been probably underestimated. This review is intended to discuss the epidemiology and risk factors of lupus retinopathy.

Address: Ophthalmology Department, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.; Rheumatology Department, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
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