Secondary Metabolites from Genus as Biopesticides and Innovative Nano-Based Application Strategies.

Bianca Ivănescu, Ana Flavia Burlec, Florina Crivoi, Crăița Roșu, Andreia Corciovă

Journal: Molecules (Basel, Switzerland) 2021;26(10):3061

PMID: 34065533

Abstract

The genus includes a large number of species with worldwide distribution and diverse chemical composition. The secondary metabolites of species have numerous applications in the health, cosmetics, and food sectors. Moreover, many compounds of this genus are known for their antimicrobial, insecticidal, parasiticidal, and phytotoxic properties, which recommend them as possible biological control agents against plant pests. This paper aims to evaluate the latest available information related to the pesticidal properties of compounds and extracts and their potential use in crop protection. Another aspect discussed in this review is the use of nanotechnology as a valuable trend for obtaining pesticides. Nanoparticles, nanoemulsions, and nanocapsules represent a more efficient method of biopesticide delivery with increased stability and potency, reduced toxicity, and extended duration of action. Given the negative impact of synthetic pesticides on human health and on the environment, -derived biopesticides and their nanoformulations emerge as promising ecofriendly alternatives to pest management.

Address: Department of Pharmaceutical Botany, Faculty of Pharmacy, "Grigore T. Popa" University of Medicine and Pharmacy, 16 University Street, 700115 Iasi, Romania.; Department of Drug Analysis, Faculty of Pharmacy, "Grigore T. Popa" University of Medicine and Pharmacy, 16 University Street, 700115 Iasi, Romania.; Department of Pharmaceutical Physics, Faculty of Pharmacy, "Grigore T. Popa" University of Medicine and Pharmacy, 16 University Street, 700115 Iasi, Romania.; Department of Experimental and Applied Biology, Institute of Biological Research Iasi, 47 Lascăr Catargi Street, 700107 Iasi, Romania.
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