Formononetin: Biological effects and uses - A review.

Juliana Machado Dutra, Paula J P Espitia, Rejane Andrade Batista

Journal: Food chemistry 2021;359():129975

PMID: 33962193

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Abstract

Formononetin (FORM) is an isoflavone from the group of phytoestrogens that exhibits a broad spectrum of physiological effects beneficial to health through dependent and independent mechanisms of estrogen. This article aimed to present FORM main functions and future prospects for applications in different areas. Scientific publications and patents dated between 1998 and 2019 were analyzed. FORM has potential as an active compound of interest to product development for the industries of food, medicine, and cosmetics, among others. Moreover, in the medical area, this active compound has shown potential in the prevention and treatment of several diseases, including chronic ones, such as cancer, obesity, and neurodegenerative diseases.

Address: Departamento de Farmácia, Universidade Federal de Sergipe, Avenida Marechal Rondon, s/n, Cidade Universitária, CEP 49100-000 São Cristóvão, SE, Brazil.; Nutrition and Dietetics School, University of Atlántico, Atlántico, Colombia. Electronic address: [email protected].; Institute of Technology and Research of Sergipe, Rua Campo do Brito, 371, 49.020-380 Aracaju, Brazil.

DOI: 10.1016/j.foodchem.2021.129975

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MeSH Terms: Humans, Isoflavones