Gabapentin attenuates superior oblique myokymia.

Robert L Tomsak, Gregory S Kosmorsky, R John Leigh

Journal: American journal of ophthalmology 2002;133(5):721-3

PMID: 11992881

Full Text on Elsevier Science View on PubMed

Abstract

PURPOSE

To investigate therapeutic effects of oral gabapentin therapy on superior oblique myokymia.

DESIGN

Observational case series with measurement of visual acuity and eye movements before, during, and after therapy.

METHODS

Two adult patients with superior oblique myokymia, refractory to other therapies, were treated with gabapentin orally after informed consent was obtained. Eye movements were measured using the magnetic search coil technique.

RESULTS

Superior oblique myokymia completely resolved after starting gabapentin.

CONCLUSION

Gabapentin may be an effective treatment for superior oblique myokymia; a double-blind study seems justified.

Address: Department of Neurology, Case Western Reserve University, Cleveland, Ohio, USA. [email protected]

DOI: 10.1016/s0002-9394(02)01343-0

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MeSH Terms: Acetates, Administration, Oral, Adult, Amines, Cyclohexanecarboxylic Acids, Diplopia, Excitatory Amino Acid Antagonists, Eye Movements, Female, Gabapentin, Humans, Male, Middle Aged, Treatment Outcome, Trochlear Nerve Diseases, gamma-Aminobutyric Acid