Extracorporeal therapies for acute intoxications.

Steven C Borkan

Journal: Critical care clinics 2002;18(2):393-420, vii

PMID: 12053840

Full Text on Elsevier Science View on PubMed

Abstract

Intoxications frequently perturb acid-base and electrolyte status, intravascular volume, and renal function. In selected cases, extracorporeal techniques effectively restore homeostasis and augment intoxicant removal. The use of 4-methylpyrazole, an inhibitor of alcohol dehydrogenase, is a new and effective treatment for patients exposed to toxic alcohols. In this section, practical approaches to commonly encountered intoxicants and the use of extracorporeal techniques are critically reviewed.

Address: Department of Medicine, Boston University, Boston Medical Center, Renal Section, Boston, MA, USA. [email protected]

DOI: 10.1016/s0749-0704(01)00011-2

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MeSH Terms: Alcohols, Humans, Lithium Compounds, Poisoning, Salicylates, Sorption Detoxification, Substance-Related Disorders, Theophylline