Current Concepts of Cirrhotic Cardiomyopathy.

Manhal J Izzy, Lisa B VanWagner

Journal: Clinics in liver disease 2021;25(2):471-481

PMID: 33838862

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Abstract

Cirrhotic cardiomyopathy (CCM) connotes systolic and/or diastolic dysfunction in patients with end-stage liver disease in the absence of prior heart disease. Its prevalence is variable across different studies but recent data suggest that CCM may affect up to one third of liver transplant candidates. The etiology of CCM is multifactorial. CCM defining features were recently revised to improve the diagnostic and prognostic yield of CCM criteria and inform candidate selection for liver transplantation. CCM appears to increase the risk for unfavorable outcomes pre- and post-transplant. Close clinical and echocardiographic follow-up of patients with CCM may mitigate adverse cardiac outcomes.

Address: Department of Medicine, Division of Gastroenterology, Hepatology, and Nutrition, Vanderbilt University Medical Center, 1660 The Vanderbilt Clinic, Nashville, TN 37232, USA. Electronic address: [email protected].; Department of Medicine, Division of Gastroenterology and Hepatology, Northwestern University Feinberg School of Medicine, 676 North St Clair, Suite 1400, Chicago, IL 60611, USA; Department of Preventive Medicine, Division of Epidemiology, Northwestern University Feinberg School of Medicine, 676 North St Clair, Suite 1400, Chicago, IL 60611, USA.

DOI: 10.1016/j.cld.2021.01.012

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MeSH Terms: Cardiomyopathies, End Stage Liver Disease, Heart Diseases, Humans, Liver Cirrhosis, Liver Transplantation