3D printing of PEEK and its composite to increase biointerfaces as a biomedical material- A review.

Bankole I Oladapo, S Abolfazl Zahedi, Sikiru O Ismail, Francis T Omigbodun

Journal: Colloids and surfaces. B, Biointerfaces 2021;203():111726

PMID: 33865088

Abstract

Poly ether-ether-ketone (PEEK) is a polymer with better lignin biocompatibility than other polymers. It is good for biomedical engineering applications. This research summarises the outcomes of an evaluation conducted on PEEK material composites, such as cellular calcium hydroxyapatite (CHAp) for medical applications. Prospects of PEEK for medical implant are highlighted. Critical analysis and review on 3D printing of PEEK, CHAp and their biological macromolecular behaviours are presented. An electronic search was carried out on Scupos database, Google search and peer-reviewed papers published in the last ten years. Because of the extraordinary strength and biological behaviours of PEEK and its composite of CHAp, 3D-printed PEEK has several biomedical applications, and its biological macromolecular behaviour leads to health sustainability. This work highlights its biological macromolecular behaviours as a bone implant material and the optimum 3D printing process for PEEK and CHAp for medical applications. The current problems with printing PEEK and CHAp are investigated along with their possible uses. Possible solutions to improve the 3D printability of PEEK and CHAp are explained based on scientific mechanisms. This detailed report stands to benefit both scientific community and medical industry to enhance 3D printing concepts for PEEK and CHAp.

Copyright © 2021 Elsevier B.V. All rights reserved.

Address: School of Engineering and Sustainable Development, De Montfort University, UK. Electronic address: [email protected].; School of Engineering and Sustainable Development, De Montfort University, UK.; School of Physics, Engineering and Computer Science, University of Hertfordshire, AL10 9AB, England, UK.; Wolfson School of Mechanical, Electrical and Manufacturing Engineering, Loughborough University, UK.

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