Ethnomedicinal Uses, Phytochemistry and Pharmacology of Different Cichorium Species (Asteraceae): A Review.

Zahra Boghrati, Elaheh Zibaee, Zahra Ayati, Mohammad Sadegh Amiri, Mahin Ramezani, Tannaz Jamialahmadi, Seyed Ahmad Emami, Amirhossein Sahebkar

Journal: Advances in experimental medicine and biology 2021;1308():501-546

PMID: 33861457

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Abstract

Cichorium species have been used widely in traditional medicine universally. It is reported as a treatment for various respiratory and gastrointestinal disorders, as well as diabetes and rheumatism. A range of constituents including phenolic and poly phenolic compounds, fatty and organic acids and essential oils comprise the chemical composition of Cichorium species. Furthermore, modern investigations on these species has shown different pharmacological activities such as antioxidant, antiproliferative, anti-inflammation, antibacterial, anti-hyperglycemic, antidiabetic and hepatoprotective effects which are associated with divers molecular pathways and mechanisms. In this chapter, we have summarized comprehensive information regarding traditional and ethnomedicinal uses, phytochemical analysis and pharmacological aspects of Cichorium species.

Address: Department of Traditional Pharmacy, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.; Department of Biology, Payame Noor University, Tehran, Iran.; Nanotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.; Department of Food Science and Technology, Quchan Branch, Islamic Azad University, Quchan, Iran.; Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.; Department of Traditional Pharmacy, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran. [email protected].; Applied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran. [email protected].; Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran. [email protected].; School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran. [email protected].; Polish Mother's Memorial Hospital Research Institute (PMMHRI), Lodz, Poland. [email protected].

DOI: 10.1007/978-3-030-64872-5_26

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https://dx.doi.org/10.1007/978-3-030-64872-5_26

MeSH Terms: Asteraceae, Ethnopharmacology, Medicine, Traditional, Phytochemicals, Phytotherapy, Plant Extracts