Alisma genus: Phytochemical constituents, biosynthesis, and biological activities.

Lei Feng, Tian-Tian Liu, Xiao-Kui Huo, Xiang-Ge Tian, Chao Wang, Xia Lv, Jing Ning, Wen-Yu Zhao, Bao-Jing Zhang, Cheng-Peng Sun, Xiao-Chi Ma

Journal: Phytotherapy research : PTR 2021;35(4):1872-1886

PMID: 33184919

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Abstract

The genus Alisma contains 11 species distributed worldwide, of which at least two species (A. orientale [Sam.] Juzep. and A. plantago-aquatica Linn.) have been used as common herbal medicines. Secondary metabolites obtained from the genus Alisma are considered to be the material basis for the various biological functions and medicinal applications. In this review, we mainly focused on the recent investigations of secondary metabolites from plants of the genus Alisma and their biological activities, with the highlighting on the diversity of the chemical structures, the biosynthesis of interesting secondary metabolites, the biological activities, and the relationships between structures and bioactivities.

Address: Dalian Key Laboratory of Metabolic Target Characterization and Traditional Chinese Medicine Intervention, College of Pharmacy, College of Integrative Medicine, Dalian Medical University, Dalian, China.

DOI: 10.1002/ptr.6933

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MeSH Terms: Alisma, Humans, Phytochemicals, Plants, Medicinal